Answer the 2 following questions attach to this
Please careful on calculation and k-mers
K-mers & Markov Chains
Q1: For this sequence: ATTACCAGAGACGATTACG
(a) List all of the k-mers (size 3) you can derive
(b) For each k-mer, list how many times it appears in the sequence
(c) Given the information above, how many unique k-mers (size 3) are there in this sequence?
Q2: Given the following matrix showing empirically-determined mutation frequencies:
|
|
A |
T |
C |
G |
|
A |
0.9 |
0.004 |
0.03 |
0.05 |
|
T |
0.015 |
0.9 |
0.02 |
0.02 |
|
C |
0.015 |
0.02 |
0.9 |
0.005 |
|
G |
0.07 |
0.004 |
0.05 |
0.9 |
(a) Draw the digraph (directed graph) showing the possible state transitions, with accompanying frequencies
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